5GMZ
Hepatitis B virus core protein Y132A mutant in complex with 4-methyl heteroaryldihydropyrimidine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Core protein | polymer | 155 | 17486.9 | 6 | UniProt (L7R9I1) UniProt (by SIFTS) (P03147) | Hepatitis B virus (HBV) | |
| 2 | G, H, I, J, O... (A, C, D, E) | ISOPROPYL ALCOHOL | non-polymer | 60.1 | 11 | Chemie (IPA) | |||
| 3 | AA, K, L, N, P... (F, A, B, C, D...) | (2S)-4,4-difluoro-1-[[(4S)-4-(4-fluorophenyl)-5-methoxycarbonyl-4-methyl-2-(1,3-thiazol-2-yl)-1H-pyrimidin-6-yl]methyl]pyrrolidine-2-carboxylic acid | non-polymer | 494.5 | 7 | Chemie (6XU) PubChem (71739468) | |||
| 4 | M, Z (B, F) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 5 | S (D) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 6 | BA, CA, DA, EA, FA... (A, B, C, D, E...) | water | water | 18.0 | 744 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 149 (UniProt: L7R9I1)
| PDB | External Database | Details |
|---|---|---|
| Ala 132 | Tyr 132 | engineered mutation |
| Glu 150 | - | expression tag |
| Asn 151 | - | expression tag |
| Leu 152 | - | expression tag |
| Tyr 153 | - | expression tag |
| Phe 154 | - | expression tag |
| Gln 155 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 104921.5 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 4342.1 | |
| All* | Total formula weight | 109263.6 |
