5G64
The complex between human IgE-Fc and two anti-IgE Fab fragments
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | IG EPSILON CHAIN C REGION | polymer | 327 | 36354.8 | 2 | HOMO SAPIENS (HUMAN) | IMMUNOGLOBULIN E | |
| 2 | C, D (H, I) | FAB FRAGMENT | polymer | 230 | 24672.5 | 2 | HOMO SAPIENS (HUMAN) | ||
| 3 | E, F (L, M) | FAB FRAGMENT | polymer | 218 | 24005.4 | 2 | HOMO SAPIENS (HUMAN) | ||
| 4 | G, H (C, D) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 2 | In PDB GlyTouCan (G22768VO) |
Sequence modifications
A, B: 222 - 547 (PDB: 5G64)
| PDB | External Database | Details |
|---|---|---|
| Asp 222 | - | expression tag |
| Ile 223 | - | expression tag |
| Val 224 | - | expression tag |
| Ala 225 | - | expression tag |
| Gln 265 | Asn 146 | engineered mutation |
| Gln 371 | Asn 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 170065.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1821.6 | |
| All* | Total formula weight | 171887.0 |
