5G08
Crystal structure of Drosophila NCS-1 bound to chlorpromazine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FREQUENIN 2 | polymer | 187 | 21922.4 | 1 | UniProt (Q9VWX8) Pfam (PF00036) Pfam (PF13499) | DROSOPHILA MELANOGASTER (FRUIT FLY) | |
| 2 | B, C, D (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 3 | E (A) | 3-(2-chloro-10H-phenothiazin-10-yl)-N,N-dimethylpropan-1-amine | non-polymer | 318.9 | 1 | Chemie (Z80) | |||
| 4 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | I (A) | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
A: 1 - 187 (UniProt: Q9VWX8)
| PDB | External Database | Details |
|---|---|---|
| Met 178 | Ile 178 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21922.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 685.4 | |
| All* | Total formula weight | 22607.8 |
