5FYM
Crystal structure of JmjC domain of human histone demethylase UTY in complex with D-2-hydroxyglutarate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HISTONE DEMETHYLASE UTY | polymer | 478 | 55006.4 | 2 | UniProt (O14607) Pfam (PF02373) Pfam (PF21322) Pfam (PF21326) | HOMO SAPIENS (HUMAN) | UBIQUITOUSLY-TRANSCRIBED TPR PROTEIN ON THE Y CHROMOSOME, UBIQUITOUSLY-TRANSCRIBED Y CHROMOSOME TETRATRICOPEPTIDE REPEAT PROTEIN |
| 2 | C, T (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | D, U (A, B) | (2R)-2-hydroxypentanedioic acid | non-polymer | 148.1 | 2 | Chemie (2HG) | |||
| 4 | AA, BA, CA, DA, E... (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 28 | Chemie (EDO) | |||
| 5 | JA, S (B, A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | KA, LA (A, B) | water | water | 18.0 | 639 | Chemie (HOH) |
Sequence modifications
A, B: 799 - 1268 (UniProt: O14607)
| PDB | External Database | Details |
|---|---|---|
| Met 798 | - | expression tag |
| Ala 1269 | - | expression tag |
| Glu 1270 | - | expression tag |
| Asn 1271 | - | expression tag |
| Leu 1272 | - | expression tag |
| Tyr 1273 | - | expression tag |
| Phe 1274 | - | expression tag |
| Gln 1275 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 110012.8 | |
| Non-Polymers* | Number of molecules | 34 |
| Total formula weight | 2274.8 | |
| All* | Total formula weight | 112287.6 |
