Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 4002 |
| Chain | Residue |
| A | CYS1199 |
| A | CYS1202 |
| A | CYS1226 |
| A | CYS1229 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 4002 |
| Chain | Residue |
| B | CYS1199 |
| B | CYS1202 |
| B | CYS1226 |
| B | CYS1229 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 2273 |
| Chain | Residue |
| B | GLU1016 |
| B | HIS1094 |
| B | 2HG2274 |
| B | HOH3137 |
| B | HIS1014 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 2266 |
| Chain | Residue |
| A | HIS1014 |
| A | GLU1016 |
| A | HIS1094 |
| A | 2HG2267 |
| A | HOH3145 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 2HG A 2267 |
| Chain | Residue |
| A | LYS1005 |
| A | THR1011 |
| A | HIS1014 |
| A | GLU1016 |
| A | SER1022 |
| A | ASN1024 |
| A | TRP1034 |
| A | HIS1094 |
| A | ALA1106 |
| A | MN2266 |
| A | EDO2278 |
| A | HOH3140 |
| A | HOH3145 |
| A | HOH3316 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE 2HG B 2274 |
| Chain | Residue |
| B | LYS1005 |
| B | THR1011 |
| B | HIS1014 |
| B | GLU1016 |
| B | SER1022 |
| B | ASN1024 |
| B | TRP1034 |
| B | HIS1094 |
| B | ALA1106 |
| B | MN2273 |
| B | EDO2282 |
| B | HOH3130 |
| B | HOH3131 |
| B | HOH3137 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 2275 |
| Chain | Residue |
| B | ILE888 |
| B | TRP889 |
| B | ARG890 |
| B | ASN1052 |
| B | HOH3308 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO A 2268 |
| Chain | Residue |
| A | SER853 |
| A | THR854 |
| A | GLN907 |
| A | GLY1028 |
| A | PRO1029 |
| A | ASN1103 |
| A | EDO2269 |
| A | EDO2273 |
| A | HOH3039 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 2269 |
| Chain | Residue |
| A | PRO1029 |
| A | TRP1101 |
| A | EDO2268 |
| A | EDO2275 |
| A | HOH3083 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 2270 |
| Chain | Residue |
| A | ARG1077 |
| A | HOH3004 |
| B | ASN919 |
| B | GLU920 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 2271 |
| Chain | Residue |
| A | HIS1188 |
| A | HIS1197 |
| A | TYR1222 |
| A | VAL1224 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 2272 |
| Chain | Residue |
| A | GLY840 |
| A | ALA842 |
| A | GLY843 |
| A | PRO1082 |
| A | GLY1083 |
| A | ASP1084 |
| A | HOH3318 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 2276 |
| Chain | Residue |
| A | LYS816 |
| B | VAL1044 |
| B | ASP1047 |
| B | PHE1048 |
| B | ALA1071 |
| B | HOH3309 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 2277 |
| Chain | Residue |
| B | PHE911 |
| B | PRO1029 |
| B | TRP1101 |
| B | EDO2278 |
| B | HOH3085 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 2278 |
| Chain | Residue |
| B | SER853 |
| B | THR854 |
| B | PRO1029 |
| B | ASN1103 |
| B | EDO2277 |
| B | EDO2286 |
| B | HOH3033 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 2273 |
| Chain | Residue |
| A | ILE1027 |
| A | EDO2268 |
| A | HOH3319 |
| A | GLY850 |
| site_id | BC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 2279 |
| Chain | Residue |
| B | LEU971 |
| B | THR972 |
| B | ARG979 |
| B | VAL980 |
| B | VAL981 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 2280 |
| Chain | Residue |
| B | HIS864 |
| B | ASP957 |
| B | ASP960 |
| B | LYS963 |
| B | HOH3046 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 2281 |
| Chain | Residue |
| B | LYS1128 |
| B | SER1131 |
| B | CYS1202 |
| B | HOH3208 |
| site_id | CC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO B 2282 |
| Chain | Residue |
| B | GLY996 |
| B | GLN1001 |
| B | TYR1003 |
| B | GLU1016 |
| B | SER1022 |
| B | ALA1106 |
| B | TRP1107 |
| B | ASN1108 |
| B | 2HG2274 |
| B | HOH3129 |
| site_id | CC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 2274 |
| Chain | Residue |
| A | THR829 |
| A | CYS1021 |
| A | ASN1089 |
| A | PRO1111 |
| A | THR1113 |
| A | CYS1115 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 2275 |
| Chain | Residue |
| A | PRO1029 |
| A | GLY1030 |
| A | GLY1100 |
| A | TRP1101 |
| A | EDO2269 |
| A | HOH3320 |
| site_id | CC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 2283 |
| Chain | Residue |
| A | ARG1081 |
| B | SER914 |
| B | GLU918 |
| site_id | CC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EDO A 2276 |
| Chain | Residue |
| A | PRO831 |
| A | GLU1039 |
| A | ASN1089 |
| A | ALA1090 |
| A | THR1092 |
| A | CYS1115 |
| A | LEU1119 |
| A | HOH3160 |
| A | HOH3161 |
| A | HOH3163 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 2284 |
| Chain | Residue |
| A | GLU863 |
| A | HOH3046 |
| B | ASN1214 |
| B | GLU1215 |
| B | THR1218 |
| B | HOH3313 |
| site_id | CC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 2285 |
| Chain | Residue |
| B | HIS1225 |
| B | THR1233 |
| B | HOH3314 |
| site_id | CC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 2286 |
| Chain | Residue |
| B | SER853 |
| B | ILE1027 |
| B | GLY1028 |
| B | PRO1029 |
| B | EDO2278 |
| site_id | DC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 2287 |
| Chain | Residue |
| B | THR829 |
| B | CYS1021 |
| B | ASN1089 |
| B | PRO1111 |
| B | THR1113 |
| B | CYS1115 |
| B | GLN1116 |
| site_id | DC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 2288 |
| Chain | Residue |
| B | PRO1029 |
| B | GLY1030 |
| B | GLY1100 |
| B | TRP1101 |
| B | HOH3315 |
| site_id | DC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 2277 |
| Chain | Residue |
| A | GLN1170 |
| A | HIS1227 |
| A | ASP1228 |
| A | HOH3236 |
| A | HOH3321 |
| B | THR1259 |
| B | LEU1260 |
| site_id | DC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO A 2278 |
| Chain | Residue |
| A | GLY996 |
| A | GLN1001 |
| A | TYR1003 |
| A | ALA1106 |
| A | TRP1107 |
| A | ASN1108 |
| A | 2HG2267 |
| A | HOH3145 |
| site_id | DC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 2279 |
| Chain | Residue |
| A | HIS825 |
| A | ALA976 |
| A | PHE977 |
| A | SER982 |
| A | GLY984 |
| A | HOH3322 |
| site_id | DC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 2280 |
| Chain | Residue |
| A | LYS803 |
| A | TYR1041 |
| A | ASN1072 |
| site_id | DC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 2281 |
| Chain | Residue |
| A | ILE811 |
| A | PRO823 |
| A | LEU824 |
| A | HOH3021 |
| A | HOH3323 |
