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5FUZ

Extending the half-life of a Fab fragment through generation of a humanised anti-Human Serum Albumin (HSA) Fv domain: an investigation into the correlation between affinity and serum half-life

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(H)
645 FAB, HEAVY CHAINpolymer23324900.91HOMO SAPIENS (HUMAN)
2B
(L)
645 FAB, LIGHT CHAINpolymer21723419.91HOMO SAPIENS (HUMAN)
3C, D
(H, L)
waterwater18.037Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight48320.8
All*Total formula weight48320.8
*Water molecules are not included.

238895

PDB entries from 2025-07-16

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