5FUY
catalytic domain of Thymidine kinase from Trypanosoma brucei with dTMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | THYMDINE KINASE | polymer | 183 | 20574.5 | 6 | UniProt (Q38CF2) Pfam (PF00265) | TRYPANOSOMA BRUCEI | |
| 2 | G, J, M, P, S... (A, B, C, D, E...) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 3 | H, K, N, Q, T... (A, B, C, D, E...) | [(2R,3S,5R)-3-HYDROXY-5-[(5S)-5-METHYL-2,4-DIOXO-1,3-DIAZINAN-1-YL]OXOLAN-2-YL]METHYL DIHYDROGEN PHOSPHATE | non-polymer | 324.2 | 6 | Chemie (QBT) | |||
| 4 | I, L, O, R, U... (A, B, C, D, E...) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 5 | AA, BA, CA, DA, Y... (C, D, E, F, A...) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 203 - 384 (UniProt: Q38CF2)
| PDB | External Database | Details |
|---|---|---|
| Ala 385 | - | expression tag |
| Asp 292 | Gly 292 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 123446.7 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2907.6 | |
| All* | Total formula weight | 126354.4 |
