5FUO
Extending the half-life of a Fab fragment through generation of a humanised anti-Human Serum Albumin (HSA) Fv domain: an investigation into the correlation between affinity and serum half-life
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | SERUM ALBUMIN | polymer | 585 | 66571.2 | 1 | UniProt (P02768) Pfam (PF00273) In PDB | HOMO SAPIENS (HUMAN) | FAB645-HSA |
| 2 | H | FAB HEAVY CHAIN | polymer | 233 | 24900.9 | 1 | HOMO SAPIENS (HUMAN) | ||
| 3 | L | FAB LIGHT CHAIN | polymer | 217 | 23419.9 | 1 | HOMO SAPIENS (HUMAN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 114892.0 | |
| All* | Total formula weight | 114892.0 |
