5FPN
Structure of heat shock-related 70kDA protein 2 with small-molecule ligand 3,5-dimethyl-1H-pyrazole-4-carboxylic acid (AT9084) in an alternate binding site.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HEAT SHOCK-RELATED 70 KDA PROTEIN 2 | polymer | 640 | 70236.0 | 2 | UniProt (P54652) Pfam (PF00012) | HOMO SAPIENS (HUMAN) | |
| 2 | C, D, E, F (A, B) | 3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID | non-polymer | 140.1 | 4 | Chemie (KYD) | |||
| 3 | G, H (A, B) | water | water | 18.0 | 829 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 638 (UniProt: P54652)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| His 1 | - | expression tag |
| Met 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 140472.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 560.6 | |
| All* | Total formula weight | 141032.5 |
