5FP7
Crystal structure of human KDM4D in complex with 3-4-methylthiophen-2- yl methylaminopyridine-4-carboxylic acid
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | LYSINE-SPECIFIC DEMETHYLASE 4D | polymer | 334 | 38534.6 | 1 | UniProt (Q6B0I6) Pfam (PF02375) Pfam (PF02373) In PDB | HOMO SAPIENS (HUMAN) | JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3D, JUMONJI DOMAIN-CONTAINING PROTEIN 2D, HUMAN LYSINE-SPECIFIC DEMETHYLASE 4D, JMJD2D |
2 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
3 | A | FE (II) ION | non-polymer | 55.8 | 1 | Chemie (FE2) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
5 | A | 3-(4-phenylbutanoylamino)pyridine-4-carboxylic acid | non-polymer | 284.3 | 1 | Chemie (YC8) | |||
6 | A | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
7 | water | water | 18.0 | 456 | Chemie (HOH) |
Sequence modifications
A: 11 - 341 (UniProt: Q6B0I6)
PDB | External Database | Details |
---|---|---|
Gly 8 | - | expression tag |
His 9 | - | expression tag |
Met 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 38534.6 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 1354.3 | |
All* | Total formula weight | 39888.9 |