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5FKO

TetR(D) E147A mutant in complex with anhydrotetracycline and magnesium

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
TETRACYCLINE REPRESSOR, CLASS D, E147A MUTANTpolymer20723230.31UniProt (C6G9U5)
Pfam (PF00440)
Pfam (PF02909)
UniProt (by SIFTS) (P0ACT4)
ESCHERICHIA COLI
2B
(A)
5A,6-ANHYDROTETRACYCLINEnon-polymer426.41Chemie (TDC)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D, E, F, G, H
(A)
CHLORIDE IONnon-polymer35.55Chemie (CL)
5I
(A)
waterwater18.0107Chemie (HOH)
Sequence modifications
A: 3 - 208 (UniProt: C6G9U5)
PDBExternal DatabaseDetails
Ser 2-expression tag
Ala 147Glu 147engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight23230.3
Non-Polymers*Number of molecules7
Total formula weight628.0
All*Total formula weight23858.3
*Water molecules are not included.

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PDB entries from 2025-06-25

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