5FIR

Crystal structure of C. elegans XRN2 in complex with the XRN2-binding domain of PAXT-1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (A, C, E, G, I...)	5'-3' EXORIBONUCLEASE 2 HOMOLOG	polymer	636	74909.1	6	UniProt (Q9U299) Pfam (PF03159) Pfam (PF17846)	CAENORHABDITIS ELEGANS
2	B, D, F, H, J... (B, D, F, H, J...)	PAXT-1	polymer	78	8988.9	6	UniProt (Q21738) Pfam (PF11952)	CAENORHABDITIS ELEGANS
3	AA, BA, CA, DA, EA... (E, G, I, K, A...)	SULFATE ION	non-polymer		96.1	27	Chemie (SO4)
4	NA, OA, PA, QA, RA... (A, B, C, E, F...)	water	water		18.0	53	Chemie (HOH)

Sequence modifications

A, C, E, G, I, K: 2 - 787 (UniProt: Q9U299)

PDB	External Database	Details
Mse 1	-	initiating methionine
-	Pro 258	deletion
-	Asn 259	deletion
-	Gln 260	deletion
-	Pro 261	deletion
-	Arg 262	deletion
-	Ala 263	deletion
-	Cys 264	deletion
-	Asp 265	deletion
-	Leu 266	deletion
-	Cys 267	deletion
-	Gly 268	deletion
-	Gln 269	deletion
-	Tyr 270	deletion
-	Gly 271	deletion
-	His 272	deletion
-	Glu 273	deletion
-	Leu 274	deletion
-	Lys 275	deletion
-	Glu 276	deletion
-	Cys 277	deletion
-	Arg 278	deletion
-	Gly 279	deletion
-	Ala 280	deletion
-	Glu 281	deletion
-	Asn 282	deletion
-	Glu 283	deletion
-	Thr 284	deletion
-	Asp 285	deletion
-	Leu 286	deletion
-	Gly 287	deletion
-	Asp 288	deletion
-	Asp 289	deletion
-	Tyr 290	deletion
-	Cys 291	deletion
-	Lys 292	deletion
-	Pro 293	deletion
-	Glu 294	deletion
-	Arg 418	deletion
-	Asn 419	deletion
-	Lys 420	deletion
-	Lys 421	deletion
-	Ala 422	deletion
-	Arg 423	deletion
-	Met 424	deletion
-	Gln 425	deletion
-	Met 426	deletion
-	Tyr 427	deletion
-	Gly 428	deletion
-	Gly 429	deletion
-	Gly 430	deletion
-	Gly 431	deletion
-	Arg 432	deletion
-	Gly 433	deletion
-	Gly 434	deletion
-	Arg 435	deletion
-	Gly 436	deletion
-	Arg 437	deletion
-	Gly 438	deletion
-	Arg 439	deletion
-	Gly 440	deletion
-	Arg 441	deletion
-	Gly 442	deletion
-	Gln 443	deletion
-	Gln 444	deletion
-	Pro 445	deletion
-	Ala 446	deletion
-	Phe 447	deletion
-	Val 448	deletion
-	Pro 449	deletion
-	Thr 450	deletion
-	His 451	deletion
-	Gly 452	deletion
-	Ile 453	deletion
-	Leu 454	deletion
-	Ala 455	deletion
-	Pro 456	deletion
-	Met 457	deletion
-	Ala 458	deletion
-	Ala 459	deletion
-	Pro 460	deletion
-	Met 461	deletion
-	His 462	deletion
-	His 463	deletion
-	Ser 464	deletion
-	Gly 465	deletion
-	Glu 466	deletion
-	Ser 467	deletion
-	Thr 468	deletion
-	Arg 469	deletion
-	Gln 470	deletion
-	Met 471	deletion
-	Ala 472	deletion
-	Ser 473	deletion
-	Glu 474	deletion
-	Ala 475	deletion
-	Arg 476	deletion
-	Gln 477	deletion
-	Thr 478	deletion
-	Ala 479	deletion
-	Met 480	deletion
-	Lys 481	deletion
-	Phe 482	deletion
-	Thr 483	deletion
-	Asn 484	deletion
-	Asp 485	deletion
-	Ala 486	deletion
-	Asn 487	deletion
-	Glu 488	deletion
-	Thr 489	deletion
-	Ala 490	deletion
-	Ala 491	deletion
-	Ala 492	deletion
-	Asn 493	deletion
-	Leu 494	deletion
-	Lys 495	deletion
-	Ala 496	deletion
-	Leu 497	deletion
-	Leu 498	deletion
-	Asn 499	deletion
-	Val 500	deletion
-	Lys 501	deletion
-	Gly 502	deletion
-	Glu 503	deletion
-	Glu 504	deletion
-	Ser 505	deletion
-	Pro 506	deletion
-	Ala 507	deletion
-	Asp 508	deletion
-	Ile 509	deletion
-	Ala 510	deletion
-	Ser 511	deletion
-	Arg 512	deletion
-	Lys 513	deletion
-	Arg 514	deletion
-	Lys 515	deletion
-	Ala 516	deletion
-	Glu 517	deletion
-	Gln 518	deletion
-	Pro 519	deletion
-	Leu 520	deletion
-	Ile 521	deletion
-	Lys 522	deletion
-	Pro 523	deletion
-	Glu 524	deletion
-	Glu 525	deletion
-	Glu 526	deletion
-	Glu 527	deletion
-	Asp 528	deletion
-	Glu 529	deletion
-	Gly 530	deletion
-	Pro 531	deletion

B, D, F, H, J, L: 2 - 75 (UniProt: Q21738)

PDB	External Database	Details
Gly -2	-	expression tag
Gly -1	-	expression tag
Gly 0	-	expression tag
Arg 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	503387.7
Non-Polymers*	Number of molecules	27
	Total formula weight	2593.7
All*	Total formula weight	505981.4

*Water molecules are not included.