5FHC
Crystal Structure of Protective Human Antibodies 100 and 114 in Complex with Ebola Virus Fusion Glycoprotein (GP)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (J) | Envelope glycoprotein | polymer | 98 | 10968.5 | 1 | UniProt (Q05320) Pfam (PF22307) | Zaire ebolavirus (strain Mayinga-76) (ZEBOV) | GP1,2,GP |
| 2 | B (K) | Envelope glycoprotein,Envelope glycoprotein | polymer | 322 | 36316.1 | 1 | UniProt (Q05320) Pfam (PF01611) | Zaire ebolavirus (ZEBOV) | GP1,2,GP,GP1,2,GP |
| 3 | C (A) | Antibody 100 Fab heavy chain | polymer | 227 | 24234.0 | 1 | Homo sapiens (human) | ||
| 4 | D (B) | Antibody 100 Fab light chain | polymer | 207 | 22255.6 | 1 | Homo sapiens (human) | ||
| 5 | E (L) | Antibody 114 Fab light chain | polymer | 212 | 22942.5 | 1 | Homo sapiens (human) | ||
| 6 | F (H) | Antibody 114 Fab heavy chain | polymer | 220 | 23203.1 | 1 | Homo sapiens (human) |
Sequence modifications
K: 1 - 308 (UniProt: Q05320)
K: 311 - 322 (UniProt: Q05320)
K: 311 - 322 (UniProt: Q05320)
| PDB | External Database | Details |
|---|---|---|
| Ser 309 | - | linker |
| Arg 310 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 139919.8 | |
| All* | Total formula weight | 139919.8 |
