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5FHC

Crystal Structure of Protective Human Antibodies 100 and 114 in Complex with Ebola Virus Fusion Glycoprotein (GP)

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH
ChainResidueDetails
HTYR194-HIS200
LTYR192-HIS198
ATYR194-HIS200
BTYR191-HIS197

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsSITE: Involved in receptor recognition and/or post-binding events => ECO:0000255
ChainResidueDetails
KLEU57
KLEU63
KARG64
KPHE88
KLYS95
KILE170

site_idSWS_FT_FI2
Number of Residues1
DetailsSITE: Cleavage; by host furin => ECO:0000269|PubMed:9576958
ChainResidueDetails
KARG322

site_idSWS_FT_FI3
Number of Residues7
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255
ChainResidueDetails
KASN40
KASN204
KASN228
KASN238
KASN257
KASN268
KASN296

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PDB entries from 2025-06-18

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