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5FFY

Crystal structure of the bromodomain of human BRPF1 in complex with a benzimidazole ligand

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Peregrinpolymer11613703.71UniProt (P55201)
Pfam (PF00439)
Homo sapiens (Human)Bromodomain and PHD finger-containing protein 1,Protein Br140
2B
(A)
4-ethyl-~{N}-(6-methoxy-1,3-dimethyl-2-oxidanylidene-benzimidazol-5-yl)benzenesulfonamidenon-polymer375.41Chemie (5XD)
3C
(A)
waterwater18.0124Chemie (HOH)
Sequence modifications
A: 626 - 740 (UniProt: P55201)
PDBExternal DatabaseDetails
Ser 625-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight13703.7
Non-Polymers*Number of molecules1
Total formula weight375.4
All*Total formula weight14079.1
*Water molecules are not included.

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PDB entries from 2024-10-30

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