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5FCT

Mouse thymidylate synthase in ternary complex with FdUMP and methylenetetrahydrofolate.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Thymidylate synthasepolymer30735001.02UniProt (Q544L2)
Pfam (PF00303)
UniProt (by SIFTS) (P07607)
Mus musculus (House Mouse)Thymidylate synthase,isoform CRA_b
2C, E
(A, B)
5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATEnon-polymer326.22Chemie (UFP)
PubChem (1816)
PubChem (8642)
PubChem (46936787)
PubChem (57318986)
PubChem (448692)
PubChem (71591612)
PubChem (449405)
PubChem (74764312)
PubChem (92209653)
PubChem (92436699)
PubChem (92436700)
PubChem (162744203)
3D, F
(A, B)
5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACIDnon-polymer459.52Chemie (C2F)
4G, H
(A, B)
waterwater18.0661Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight70002.0
Non-Polymers*Number of molecules4
Total formula weight1571.3
All*Total formula weight71573.3
*Water molecules are not included.

253389

PDB entries from 2026-05-13

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