5FCA

Murine SMPDL3A in presence of excess zinc

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Acid sphingomyelinase-like phosphodiesterase 3a	polymer	433	48997.3	2	UniProt (P70158) Pfam (PF00149) Pfam (PF19272) In PDB	Mus musculus (Mouse)	ASM-like phosphodiesterase 3a
2	C, F, G, J	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		570.5	4	In PDB GlyTouCan (G21290RB)
3	D, H	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
4	E, I	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	2	In PDB GlyTouCan (G22768VO)
5	A, B	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
6	B, A	GLYCEROL	non-polymer		92.1	13	Chemie (GOL)
7		water	water		18.0	808	Chemie (HOH)

Sequence modifications

A, B: 23 - 445 (UniProt: P70158)

PDB	External Database	Details
Asp 13	-	expression tag
Arg 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
Lys 21	-	expression tag
Leu 22	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	97994.5
Branched	Number of molecules	8
	Total formula weight	4952.6
Non-Polymers*	Number of molecules	21
	Total formula weight	1720.5
All*	Total formula weight	104667.6

*Water molecules are not included.