5FCA

Murine SMPDL3A in presence of excess zinc

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004767	molecular_function	sphingomyelin phosphodiesterase activity
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0006685	biological_process	sphingomyelin catabolic process
A	0008081	molecular_function	phosphoric diester hydrolase activity
A	0008270	molecular_function	zinc ion binding
A	0009143	biological_process	nucleoside triphosphate catabolic process
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
A	0046872	molecular_function	metal ion binding
A	0160049	biological_process	negative regulation of cGAS/STING signaling pathway
B	0004767	molecular_function	sphingomyelin phosphodiesterase activity
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0006685	biological_process	sphingomyelin catabolic process
B	0008081	molecular_function	phosphoric diester hydrolase activity
B	0008270	molecular_function	zinc ion binding
B	0009143	biological_process	nucleoside triphosphate catabolic process
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0017111	molecular_function	ribonucleoside triphosphate phosphatase activity
B	0046872	molecular_function	metal ion binding
B	0160049	biological_process	negative regulation of cGAS/STING signaling pathway

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26792860","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"26792860","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	10
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"26792860","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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