5F6B
Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.3 Angstrom Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Retinol-binding protein 2 | polymer | 133 | 15609.5 | 2 | UniProt (P50120) Pfam (PF00061) | Homo sapiens (Human) | Cellular retinol-binding protein II,CRBP-II |
| 2 | C, E (A, B) | RETINAL | non-polymer | 284.4 | 2 | Chemie (RET) PubChem (1070) PubChem (23254473) PubChem (177675058) PubChem (638015) PubChem (5353924) PubChem (6436079) PubChem (6436082) PubChem (87082476) PubChem (87110449) PubChem (87110609) PubChem (88398773) PubChem (88407543) PubChem (11426127) PubChem (12227253) PubChem (12227254) PubChem (12227256) PubChem (12227257) PubChem (12227258) PubChem (12227259) PubChem (12227269) PubChem (12227270) PubChem (12227271) PubChem (5280490) PubChem (5381765) PubChem (134688327) PubChem (140510408) PubChem (145826762) PubChem (169423542) PubChem (172878320) | |||
| 3 | D, F (A, B) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) PubChem (175) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 347 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 133 (UniProt: P50120)
| PDB | External Database | Details |
|---|---|---|
| Trp 19 | Tyr 20 | engineered mutation |
| Leu 40 | Lys 41 | engineered mutation |
| Val 51 | Thr 52 | engineered mutation |
| Tyr 58 | Arg 59 | engineered mutation |
| Lys 108 | Gln 109 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 31219.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 687.0 | |
| All* | Total formula weight | 31906.0 |
