5F6B

Crystal structure of the Q108K:K40L:T51V:R58Y:Y19W mutant of human Cellular Retinol Binding Protein II in complex with All-trans-Retinal at 1.3 Angstrom Resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005501	molecular_function	retinoid binding
A	0005504	molecular_function	fatty acid binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006776	biological_process	vitamin A metabolic process
A	0008289	molecular_function	lipid binding
A	0008544	biological_process	epidermis development
A	0015908	biological_process	fatty acid transport
A	0016918	molecular_function	retinal binding
A	0019841	molecular_function	retinol binding
B	0005501	molecular_function	retinoid binding
B	0005504	molecular_function	fatty acid binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006776	biological_process	vitamin A metabolic process
B	0008289	molecular_function	lipid binding
B	0008544	biological_process	epidermis development
B	0015908	biological_process	fatty acid transport
B	0016918	molecular_function	retinal binding
B	0019841	molecular_function	retinol binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue RET A 201

Chain	Residue
A	PHE16
A	ALA33
A	THR53
A	TYR60
A	TRP106
A	LYS108
A	ACT202

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site_id	AC2
Number of Residues	6
Details	binding site for residue ACT A 202

Chain	Residue
A	GLN97
A	TRP106
A	RET201
A	HOH324
A	TYR60
A	GLU72

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site_id	AC3
Number of Residues	5
Details	binding site for residue ACT B 202

Chain	Residue
B	TYR60
B	GLU72
B	GLN97
B	TRP106
B	RET201

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:18076076

Chain	Residue	Details
A	LEU40
A	LYS108
B	LEU40
B	LYS108

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