5EZD

Crystal structure of a Hepatocyte growth factor activator inhibitor-1 (HAI-1) fragment covering the PKD-like 'internal' domain and Kunitz domain 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Kunitz-type protease inhibitor 1	polymer	145	16784.8	2	UniProt (O43278) Pfam (PF22352) Pfam (PF00014)	Homo sapiens (Human)	Hepatocyte growth factor activator inhibitor type 1,HAI-1
2	C, F (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
3	D, E (B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
4	G, H (A, B)	water	water		18.0	63	Chemie (HOH)

Sequence modifications

A, B: 168 - 303 (UniProt: O43278)

PDB	External Database	Details
Lys 166	-	expression tag
Arg 167	-	expression tag
Asp 304	-	expression tag
His 305	-	expression tag
His 306	-	expression tag
His 307	-	expression tag
His 308	-	expression tag
His 309	-	expression tag
His 310	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33569.6
Non-Polymers*	Number of molecules	4
	Total formula weight	196.3
All*	Total formula weight	33765.9

*Water molecules are not included.