5ELO
Crystal Structure of Lysyl-tRNA Synthetase from Cryptosporidium parvum complexed with L-lysine and cladosporin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Lysine--tRNA ligase | polymer | 535 | 61459.1 | 4 | UniProt (Q5CR27) Pfam (PF01336) Pfam (PF00152) | Cryptosporidium parvum (strain Iowa II) | Lysyl-tRNA synthetase |
| 2 | E, I, L, O (A, B, C, D) | LYSINE | non-polymer | 147.2 | 4 | Chemie (LYS) | |||
| 3 | F, J, M, P (A, B, C, D) | cladosporin | non-polymer | 292.3 | 4 | Chemie (KRS) | |||
| 4 | G, H, K, N, Q... (A, B, C, D) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 5 | S (D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 6 | T, U, V, W (A, B, C, D) | water | water | 18.0 | 1969 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 46 - 559 (UniProt: Q5CR27)
| PDB | External Database | Details |
|---|---|---|
| Met 25 | - | initiating methionine |
| Ala 26 | - | expression tag |
| His 27 | - | expression tag |
| His 28 | - | expression tag |
| His 29 | - | expression tag |
| His 30 | - | expression tag |
| His 31 | - | expression tag |
| His 32 | - | expression tag |
| Met 33 | - | expression tag |
| Gly 34 | - | expression tag |
| Thr 35 | - | expression tag |
| Leu 36 | - | expression tag |
| Glu 37 | - | expression tag |
| Ala 38 | - | expression tag |
| Gln 39 | - | expression tag |
| Thr 40 | - | expression tag |
| Gln 41 | - | expression tag |
| Gly 42 | - | expression tag |
| Pro 43 | - | expression tag |
| Gly 44 | - | expression tag |
| Ser 45 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 245836.4 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2396.5 | |
| All* | Total formula weight | 248232.9 |
