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5EKD

Human mitochondrial tryptophanyl-tRNA synthetase bound by indolmycin and Mn*ATP.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Tryptophan--tRNA ligase, mitochondrialpolymer34338044.02UniProt (Q9UGM6)
Pfam (PF00579)
Homo sapiens (Human)(Mt)TrpRS,Tryptophanyl-tRNA synthetase,TrpRS
2C, G
(A, B)
(5S)-5-[(1R)-1-(1H-indol-3-yl)ethyl]-2-(methylamino)-1,3-oxazol-4(5H)-onenon-polymer257.32Chemie (5BX)
3D, H
(A, B)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.22Chemie (ATP)
4E, F, I, J
(A, B)
MANGANESE (II) IONnon-polymer54.94Chemie (MN)
5K, L
(B)
GLYCEROLnon-polymer92.12Chemie (GOL)
6M, N
(A, B)
waterwater18.0541Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight76087.9
Non-Polymers*Number of molecules10
Total formula weight1932.9
All*Total formula weight78020.8
*Water molecules are not included.

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PDB entries from 2025-06-18

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