5EGS
Human PRMT6 with bound fragment-type inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Protein arginine N-methyltransferase 6 | polymer | 376 | 42074.6 | 4 | UniProt (Q96LA8) Pfam (PF13649) Pfam (PF22528) | Homo sapiens (Human) | Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6,Histone-arginine N-methyltransferase PRMT6 |
| 2 | E, H, J, M (A, B, C, D) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 4 | Chemie (SAH) | |||
| 3 | F, G, I, K, L... (A, B, C, D) | 2-[4-(phenylmethyl)piperidin-1-yl]ethanamine | non-polymer | 218.3 | 6 | Chemie (5NR) | |||
| 4 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 405 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 375 (UniProt: Q96LA8)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Val 194 | Ala 194 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 168298.2 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2847.7 | |
| All* | Total formula weight | 171145.9 |
