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5EGS

Human PRMT6 with bound fragment-type inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, DProtein arginine N-methyltransferase 6polymer37642074.64UniProt (Q96LA8)
Pfam (PF13649)
In PDB
Homo sapiens (Human)Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6,Histone-arginine N-methyltransferase PRMT6
2A, B, C, DS-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.44Chemie (SAH)
3A, B, C, D2-[4-(phenylmethyl)piperidin-1-yl]ethanaminenon-polymer218.36Chemie (5NR)
4waterwater18.0405Chemie (HOH)
Sequence modifications
A, B, C, D: 1 - 375 (UniProt: Q96LA8)
PDBExternal DatabaseDetails
Gly 0-expression tag
Val 194Ala 194conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight168298.2
Non-Polymers*Number of molecules10
Total formula weight2847.7
All*Total formula weight171145.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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