5EGO

HOXB13-MEIS1 heterodimer bound to methylated DNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Homeobox protein Meis1	polymer	57	6756.8	1	UniProt (O00470) Pfam (PF05920) In PDB	Homo sapiens (Human)
2	D	DNA (5'-D(P*GP*TP*TP*GP*AP*CP*AP*GP*TP*TP*TP*TP*AP*(5CM)P*GP*AP*GP*G)-3')	polymer	18	5600.7	1		synthetic construct
3	E	DNA (5'-D(*CP*CP*TP*(5CM)P*GP*TP*AP*AP*AP*AP*CP*TP*GP*TP*CP*AP*AP*C)-3')	polymer	18	5458.6	1		synthetic construct
4	B	Homeobox protein Hox-B13	polymer	63	7640.1	1	UniProt (Q92826) Pfam (PF00046) In PDB	Homo sapiens (Human)
5		water	water		18.0	20	Chemie (HOH)

Sequence modifications

A: 279 - 333 (UniProt: O00470)

PDB	External Database	Details
Ala 278	-	expression tag
Met 334	-	expression tag

B: 217 - 277 (UniProt: Q92826)

PDB	External Database	Details
Val 278	-	expression tag
Lys 279	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	25456.1
All*	Total formula weight	25456.1

*Water molecules are not included.