5EGE
Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Ectonucleotide pyrophosphatase/phosphodiesterase family member 6 | polymer | 429 | 49598.7 | 4 | UniProt (Q8BGN3) Pfam (PF01663) In PDB | Mus musculus (Mouse) | NPP-6,Choline-specific glycerophosphodiester phosphodiesterase,Glycerophosphocholine cholinephosphodiesterase,GPC-Cpde |
| 2 | E, G, I, K | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 4 | In PDB GlyTouCan (G28454KX) | |||
| 3 | F, H, J, L | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 4 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D, A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 7 | Chemie (NAG) | |||
| 5 | C, D, A, B | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 6 | C, D, A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 7 | water | water | 18.0 | 2048 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 421 (UniProt: Q8BGN3)
| PDB | External Database | Details |
|---|---|---|
| Ala 393 | Cys 393 | engineered mutation |
| Ser 412 | Cys 412 | engineered mutation |
| Ser 422 | - | expression tag |
| Arg 423 | - | expression tag |
| Glu 424 | - | expression tag |
| Asn 425 | - | expression tag |
| Leu 426 | - | expression tag |
| Tyr 427 | - | expression tag |
| Phe 428 | - | expression tag |
| Gln 429 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 198394.7 | |
| Branched | Number of molecules | 8 |
| Total formula weight | 3979.8 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 2444.1 | |
| All* | Total formula weight | 204818.6 |
