5EGE
Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0047390 | molecular_function | glycerophosphocholine cholinephosphodiesterase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0047390 | molecular_function | glycerophosphocholine cholinephosphodiesterase activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0047390 | molecular_function | glycerophosphocholine cholinephosphodiesterase activity |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0047390 | molecular_function | glycerophosphocholine cholinephosphodiesterase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Nucleophile => ECO:0000255 |
| Chain | Residue | Details |
| A | SER71 | |
| B | SER71 | |
| C | SER71 | |
| D | SER71 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26888014, ECO:0007744|PDB:5EGE, ECO:0007744|PDB:5EGH |
| Chain | Residue | Details |
| A | ASP32 | |
| B | ASP193 | |
| B | HIS197 | |
| B | ASP240 | |
| B | HIS241 | |
| B | HIS354 | |
| C | ASP32 | |
| C | SER71 | |
| C | ASP193 | |
| C | HIS197 | |
| C | ASP240 | |
| A | SER71 | |
| C | HIS241 | |
| C | HIS354 | |
| D | ASP32 | |
| D | SER71 | |
| D | ASP193 | |
| D | HIS197 | |
| D | ASP240 | |
| D | HIS241 | |
| D | HIS354 | |
| A | ASP193 | |
| A | HIS197 | |
| A | ASP240 | |
| A | HIS241 | |
| A | HIS354 | |
| B | ASP32 | |
| B | SER71 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:26888014, ECO:0007744|PDB:5EGH |
| Chain | Residue | Details |
| A | ASN92 | |
| B | ASN92 | |
| C | ASN92 | |
| D | ASN92 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:B0BND0 |
| Chain | Residue | Details |
| A | SER71 | |
| B | SER71 | |
| C | SER71 | |
| D | SER71 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | LIPID: GPI-anchor amidated serine => ECO:0000255 |
| Chain | Residue | Details |
| A | SER419 | |
| B | SER419 | |
| C | SER419 | |
| D | SER419 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:26888014, ECO:0007744|PDB:5EGE |
| Chain | Residue | Details |
| A | ASN100 | |
| B | ASN100 | |
| C | ASN100 | |
| D | ASN100 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:26888014, ECO:0007744|PDB:5EGE, ECO:0007744|PDB:5EGH |
| Chain | Residue | Details |
| A | ASN118 | |
| D | ASN118 | |
| D | ASN341 | |
| D | ASN404 | |
| A | ASN341 | |
| A | ASN404 | |
| B | ASN118 | |
| B | ASN341 | |
| B | ASN404 | |
| C | ASN118 | |
| C | ASN341 | |
| C | ASN404 |
