5EFQ
Crystal structure of human Cdk13/Cyclin K in complex with ADP-aluminum fluoride
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Cyclin-dependent kinase 13 | polymer | 347 | 40521.9 | 2 | UniProt (Q14004) Pfam (PF00069) | Homo sapiens (Human) | CDC2-related protein kinase 5,Cell division cycle 2-like protein kinase 5,Cell division protein kinase 13,hCDK13,Cholinesterase-related cell division controller |
| 2 | B, D (B, D) | Cyclin-K | polymer | 268 | 31429.2 | 2 | UniProt (O75909) Pfam (PF00134) Pfam (PF21797) | Homo sapiens (Human) | |
| 3 | E, I (A, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 2 | Chemie (ADP) | |||
| 4 | F, J (A, C) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 2 | Chemie (AF3) | |||
| 5 | G, H, K, L (A, C) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 6 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A, C: 694 - 1039 (UniProt: Q14004)
B, D: 1 - 267 (UniProt: O75909)
| PDB | External Database | Details |
|---|---|---|
| Gly 693 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 143902.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1119.6 | |
| All* | Total formula weight | 145021.6 |
