5EFQ

Crystal structure of human Cdk13/Cyclin K in complex with ADP-aluminum fluoride

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	Cyclin-dependent kinase 13	polymer	347	40521.9	2	UniProt (Q14004) Pfam (PF00069) In PDB	Homo sapiens (Human)	CDC2-related protein kinase 5,Cell division cycle 2-like protein kinase 5,Cell division protein kinase 13,hCDK13,Cholinesterase-related cell division controller
2	B, D	Cyclin-K	polymer	268	31429.2	2	UniProt (O75909) Pfam (PF00134) Pfam (PF21797) In PDB	Homo sapiens (Human)
3	A, C	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
4	A, C	ALUMINUM FLUORIDE	non-polymer		84.0	2	Chemie (AF3)
5	A, C	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6		water	water		18.0	289	Chemie (HOH)

Sequence modifications

A, C: 694 - 1039 (UniProt: Q14004)

PDB	External Database	Details
Gly 693	-	expression tag

B, D: 1 - 267 (UniProt: O75909)

PDB	External Database	Details
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	143902.1
Non-Polymers*	Number of molecules	8
	Total formula weight	1119.6
All*	Total formula weight	145021.6

*Water molecules are not included.