5DXA
Crystal structure of CARM1, sinefungin, and methylated PABP1 peptide (R460)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Histone-arginine methyltransferase CARM1 | polymer | 349 | 39623.1 | 4 | UniProt (Q86X55) Pfam (PF06325) Pfam (PF22528) In PDB | Homo sapiens (Human) | Coactivator-associated arginine methyltransferase 1,Protein arginine N-methyltransferase 4 |
| 2 | F, G, I | methylated PABP1 peptide | polymer | 19 | 1951.3 | 3 | UniProt (P11940) In PDB | Homo sapiens | Poly(A)-binding protein 1 |
| 3 | A, B, C, D | SINEFUNGIN | non-polymer | 381.4 | 4 | Chemie (SFG) | |||
| 4 | A, B, C | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 505 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 134 - 479 (UniProt: Q86X55)
F, G, I: 1 - 18 (UniProt: P11940)
| PDB | External Database | Details |
|---|---|---|
| Ser 131 | - | expression tag |
| Ile 132 | - | expression tag |
| Ala 133 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Nh2 19 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 164346.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1801.8 | |
| All* | Total formula weight | 166148.3 |
