5DKW

Ternary crystal structure of polymerase lambda with a GA mispair at the primer terminus with Ca2+ in the active

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	DNA polymerase lambda	polymer	327	36620.8	2	UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791)	Homo sapiens (Human)	Pol Lambda,DNA polymerase beta-2,Pol beta2,DNA polymerase kappa
2	C, F (D, C)	DNA (5'-D(P*GP*CP*CP*G)-3')	polymer	4	1191.8	2		synthetic construct
3	D, G (P, E)	DNA (5'-D(*CP*AP*GP*TP*AP*C)-3')	polymer	6	1793.2	2		synthetic construct
4	E, H (T, F)	DNA (5'-D(*CP*GP*GP*CP*GP*GP*TP*AP*CP*TP*G)-3')	polymer	11	3390.2	2		synthetic construct
5	I, N (A, B)	2'-DEOXYADENOSINE 5'-TRIPHOSPHATE	non-polymer		491.2	2	Chemie (DTP)
6	J, K, L, M, O (A, B)	CALCIUM ION	non-polymer		40.1	5	Chemie (CA)
7	P, Q, R, S, T... (A, B, D, P, T...)	water	water		18.0	205	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	85992.0
Non-Polymers*	Number of molecules	7
	Total formula weight	1182.8
All*	Total formula weight	87174.8

*Water molecules are not included.