5DEN
The First Structure of a Full-Length Mammalian Phenylalanine Hydroxylase Reveals the Architecture of an Auto-inhibited Tetramer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Phenylalanine-4-hydroxylase | polymer | 453 | 51871.6 | 4 | UniProt (P04176) Pfam (PF01842) Pfam (PF00351) | Rattus norvegicus (Rat) | PAH,Phe-4-monooxygenase |
| 2 | E, F, G, H (A, B, C, D) | FE (III) ION | non-polymer | 55.8 | 4 | Chemie (FE) | |||
| 3 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 453 (UniProt: P04176)
| PDB | External Database | Details |
|---|---|---|
| Ser 87 | Thr 87 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 207486.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 223.4 | |
| All* | Total formula weight | 207709.6 |
