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5DCZ

Tankyrase 2 complexed with a selective inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Tankyrase-2polymer23126084.51UniProt (Q9H2K2)
Pfam (PF00644)
Homo sapiens (Human)TANK2,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-like protein,Tankyrase-related protein
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
4D
(A)
morpholin-4-yl[4-(tetrazolo[1,5-a]quinoxalin-4-ylamino)phenyl]methanonenon-polymer375.41Chemie (59B)
5E
(A)
waterwater18.0116Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26084.5
Non-Polymers*Number of molecules3
Total formula weight535.8
All*Total formula weight26620.2
*Water molecules are not included.

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PDB entries from 2025-07-16

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