5D7V

Crystal structure of PTK6 kinase domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Protein-tyrosine kinase 6	polymer	269	31140.9	4	UniProt (Q13882) Pfam (PF07714)	Homo sapiens (Human)	Breast tumor kinase,Tyrosine-protein kinase BRK
2	E, I, M, Q (A, B, C, D)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
3	F, G, H, J, K... (A, B, C, D)	GLYCEROL	non-polymer		92.1	12	Chemie (GOL)
4	U, V, W, X (A, B, C, D)	water	water		18.0	366	Chemie (HOH)

Sequence modifications

A, B, C, D: 185 - 446 (UniProt: Q13882)

PDB	External Database	Details
Cxm 184	-	expression tag
Thr 433	Cys 433	engineered mutation
His 447	-	expression tag
His 448	-	expression tag
His 449	-	expression tag
His 450	-	expression tag
His 451	-	expression tag
His 452	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	124563.6
Non-Polymers*	Number of molecules	16
	Total formula weight	1485.0
All*	Total formula weight	126048.7

*Water molecules are not included.