5D75
Crystal structure of Human FKBD25 in complex with FK506
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidyl-prolyl cis-trans isomerase FKBP3 | polymer | 124 | 14031.1 | 1 | UniProt (Q00688) Pfam (PF00254) | Homo sapiens (Human) | PPIase FKBP3,25 kDa FK506-binding protein,FKBP-25,FK506-binding protein 3,FKBP-3,Immunophilin FKBP25,Rapamycin-selective 25 kDa immunophilin,Rotamase |
| 2 | B (A) | 8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN | non-polymer | 804.0 | 1 | Chemie (FK5) | |||
| 3 | C, D (A) | O-(O-(2-AMINOPROPYL)-O'-(2-METHOXYETHYL)POLYPROPYLENE GLYCOL 500) | non-polymer | 597.8 | 2 | Chemie (JEF) | |||
| 4 | E (A) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 109 - 224 (UniProt: Q00688)
| PDB | External Database | Details |
|---|---|---|
| Leu 225 | - | expression tag |
| Glu 226 | - | expression tag |
| His 227 | - | expression tag |
| His 228 | - | expression tag |
| His 229 | - | expression tag |
| His 230 | - | expression tag |
| His 231 | - | expression tag |
| His 232 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14031.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1999.7 | |
| All* | Total formula weight | 16030.8 |
