5D6F
Structure of human methionine aminopeptidase-2 complexed with spiroepoxytriazole inhibitor (+)-31b
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Methionine aminopeptidase 2 | polymer | 371 | 41510.1 | 1 | UniProt (P50579) Pfam (PF00557) | Homo sapiens (Human) | MetAP 2,Initiation factor 2-associated 67 kDa glycoprotein,p67eIF2,Peptidase M |
| 2 | B (A) | (4S,7R)-7-hydroxy-1-(4-methoxybenzyl)-7-methyl-4,5,6,7-tetrahydro-1H-benzotriazol-4-yl propan-2-ylcarbamate | non-polymer | 374.4 | 1 | Chemie (57R) | |||
| 3 | C (A) | COBALT (II) ION | non-polymer | 58.9 | 1 | Chemie (CO) | |||
| 4 | D, E (A) | TERTIARY-BUTYL ALCOHOL | non-polymer | 74.1 | 2 | Chemie (TBU) | |||
| 5 | F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | H (A) | water | water | 18.0 | 504 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41510.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 705.7 | |
| All* | Total formula weight | 42215.9 |
