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5D5H

Crystal structure of Mycobacterium tuberculosis Topoisomerase I

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA topoisomerase 1polymer70677843.51UniProt (P9WG49)
Pfam (PF01751)
Pfam (PF01131)
Pfam (PF13368)
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)DNA topoisomerase I,Omega-protein,Relaxing enzyme,Swivelase,Untwisting enzyme
2B, C, D, E, F
(A)
SULFATE IONnon-polymer96.15Chemie (SO4)
3G, H
(A)
GLYCEROLnon-polymer92.12Chemie (GOL)
4I
(A)
ACETATE IONnon-polymer59.01Chemie (ACT)
5J
(A)
waterwater18.072Chemie (HOH)
Sequence modifications
A: 2 - 704 (UniProt: P9WG49)
PDBExternal DatabaseDetails
Ser -1-expression tag
Asn 0-expression tag
Ala 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight77843.5
Non-Polymers*Number of molecules8
Total formula weight723.5
All*Total formula weight78567.0
*Water molecules are not included.

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PDB entries from 2025-06-18

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