5D46
Structural Basis for a New Templated Activity by Terminal Deoxynucleotidyl Transferase: Implications for V(D)J Recombination
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Terminal deoxynucleotidyltransferase | polymer | 400 | 45704.0 | 1 | UniProt (Q3UZ80) Pfam (PF14716) Pfam (PF10391) Pfam (PF01909) Pfam (PF14791) UniProt (by SIFTS) (P09838) In PDB | Mus musculus (Mouse) | |
2 | B, E | DNA (5'-D(*AP*AP*AP*AP*AP*A)-3') | polymer | 6 | 1810.3 | 2 | synthetic construct | ||
3 | C, D | DNA (5'-D(*TP*TP*TP*TP*TP*GP*C)-3') | polymer | 7 | 2094.4 | 2 | synthetic construct | ||
4 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
5 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
6 | A | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
7 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
8 | A | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) | |||
9 | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A: 132 - 510 (UniProt: Q3UZ80)
PDB | External Database | Details |
---|---|---|
Met 111 | - | initiating methionine |
Gly 112 | - | expression tag |
Ser 113 | - | expression tag |
Ser 114 | - | expression tag |
His 115 | - | expression tag |
His 116 | - | expression tag |
His 117 | - | expression tag |
His 118 | - | expression tag |
His 119 | - | expression tag |
His 120 | - | expression tag |
Ser 121 | - | expression tag |
Ser 122 | - | expression tag |
Gly 123 | - | expression tag |
Leu 124 | - | expression tag |
Val 125 | - | expression tag |
Pro 126 | - | expression tag |
Arg 127 | - | expression tag |
Gly 128 | - | expression tag |
Ser 129 | - | expression tag |
His 130 | - | expression tag |
Met 131 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 5 |
Total formula weight | 53513.3 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 592.5 | |
All* | Total formula weight | 54105.8 |