5CX6

Crystal structure of Thosea asigna virus RNA-dependent RNA polymerase (RdRP) complexed with CDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	RNA-dependent RNA polymerase	polymer	705	79540.5	2	UniProt (Q6A562)	Thosea asigna virus
2	AA, BA, C, D, E... (B, A)	SULFATE ION	non-polymer		96.1	12	Chemie (SO4)
3	CA, DA, EA, FA, GA... (B, A)	GLYCEROL	non-polymer		92.1	19	Chemie (GOL)
4	V (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
5	JA, W (B, A)	CYTIDINE-5'-DIPHOSPHATE	non-polymer		403.2	2	Chemie (CDP)
6	KA, LA (A, B)	water	water		18.0	603	Chemie (HOH)

Sequence modifications

A, B: 1 - 674 (UniProt: Q6A562)

PDB	External Database	Details
Met -30	-	initiating methionine
Ser -29	-	expression tag
Tyr -28	-	expression tag
Tyr -27	-	expression tag
His -26	-	expression tag
His -25	-	expression tag
His -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
Asp -20	-	expression tag
Tyr -19	-	expression tag
Asp -18	-	expression tag
Ile -17	-	expression tag
Pro -16	-	expression tag
Thr -15	-	expression tag
Thr -14	-	expression tag
Glu -13	-	expression tag
Asn -12	-	expression tag
Leu -11	-	expression tag
Tyr -10	-	expression tag
Phe -9	-	expression tag
Gln -8	-	expression tag
Gly -7	-	expression tag
Ala -6	-	expression tag
Met -5	-	expression tag
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Ile 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	159080.9
Non-Polymers*	Number of molecules	34
	Total formula weight	3733.2
All*	Total formula weight	162814.1

*Water molecules are not included.