5CM9

Structural Basis for the Selectivity of Guanine Nucleotide Exchange Factors for the small G-protein Ral

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Ral guanine nucleotide dissociation stimulator-like 2	polymer	473	52113.9	2	UniProt (Q61193) Pfam (PF00618) Pfam (PF00617) In PDB	Mus musculus (Mouse)	RalGDS-like 2,RalGDS-like factor,Ras-associated protein RAB2L
2	C, D	Ras-related protein Ral-a	polymer	203	23117.3	2	UniProt (P48555) Pfam (PF00071) In PDB	Drosophila melanogaster (Fruit fly)
3		water	water		18.0	36	Chemie (HOH)

Sequence modifications

A, B: 50 - 514 (UniProt: Q61193)

PDB	External Database	Details
Gly 42	-	expression tag
Pro 43	-	expression tag
Leu 44	-	expression tag
Gly 45	-	expression tag
Ser 46	-	expression tag
Pro 47	-	expression tag
Asn 48	-	expression tag
Ser 49	-	expression tag
Tyr 147	His 147	conflict
Thr 402	Met 402	conflict

C, D: 1 - 201 (UniProt: P48555)

PDB	External Database	Details
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	150462.4
All*	Total formula weight	150462.4

*Water molecules are not included.