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5CFN

Crystal structure of anemone STING (Nematostella vectensis) in complex with 3',3' c-di-AMP, c[A(3',5')pA(3',5')p]

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Stimulator of Interferon Genespolymer18721725.72UniProt (A7SLZ2)
Pfam (PF15009)
Nematostella vectensis (Starlet sea anemone)Predicted protein
2C, D
(A)
(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxidenon-polymer658.42Chemie (2BA)
Sequence modifications
A, B: 193 - 377 (UniProt: A7SLZ2)
PDBExternal DatabaseDetails
Gly 191-expression tag
Ser 192-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43451.4
Non-Polymers*Number of molecules2
Total formula weight1316.8
All*Total formula weight44768.3
*Water molecules are not included.

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PDB entries from 2025-12-24

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