5CFN
Crystal structure of anemone STING (Nematostella vectensis) in complex with 3',3' c-di-AMP, c[A(3',5')pA(3',5')p]
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002218 | biological_process | activation of innate immune response |
| A | 0032481 | biological_process | positive regulation of type I interferon production |
| B | 0002218 | biological_process | activation of innate immune response |
| B | 0032481 | biological_process | positive regulation of type I interferon production |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue 2BA A 401 |
| Chain | Residue |
| A | SER201 |
| B | GLY205 |
| B | TYR206 |
| B | ARG278 |
| B | TYR280 |
| B | THR303 |
| B | PRO304 |
| A | GLY205 |
| A | TYR206 |
| A | ARG278 |
| A | TYR280 |
| A | THR303 |
| A | PRO304 |
| A | 2BA402 |
| B | TYR202 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue 2BA A 402 |
| Chain | Residue |
| A | ARG278 |
| A | HIS279 |
| A | THR303 |
| A | 2BA401 |
| B | ARG278 |
| B | HIS279 |
| B | THR303 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26300263","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5CFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CFP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q86WV6","evidenceCode":"ECO:0000250"},{"source":"PubMed","id":"26300263","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5CFL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5CFP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26300263","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5CFQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
