5CFM
Crystal structure of anemone STING (Nematostella vectensis) in complex with 3', 3' cGAMP, c[G(3', 5')pA(3', 5')p]
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Stimulator of Interferon Genes | polymer | 187 | 21725.7 | 2 | UniProt (A7SLZ2) Pfam (PF15009) | Nematostella vectensis (Starlet sea anemone) | Predicted protein |
| 2 | C (A) | 2-amino-9-[(2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-9-(6-amino-9H-purin-9-yl)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecin-2-yl]-1,9-dihydro-6H-purin-6-one | non-polymer | 674.4 | 1 | Chemie (4BW) PubChem (135518383) PubChem (136969326) PubChem (137222342) PubChem (146666430) PubChem (146721591) PubChem (163926673) PubChem (164708339) PubChem (170530654) PubChem (135471108) PubChem (135566855) PubChem (137014984) PubChem (138107821) PubChem (146721594) PubChem (167377552) PubChem (168281482) PubChem (170530664) PubChem (170997023) | |||
| 3 | D, E, F, G (A, B) | CITRATE ANION | non-polymer | 189.1 | 4 | Chemie (FLC) PubChem (31348) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 256 | Chemie (HOH) |
Sequence modifications
A, B: 193 - 377 (UniProt: A7SLZ2)
| PDB | External Database | Details |
|---|---|---|
| Gly 191 | - | expression tag |
| Ser 192 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43451.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1430.8 | |
| All* | Total formula weight | 44882.3 |
