5CCV

Crystal structure of full-length NS5 from dengue virus type 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	RNA-directed RNA polymerase NS5	polymer	905	104140.0	8	UniProt (P27915)	Dengue virus type 3 (DENV-3)	Non-structural protein 5
2	AA, BA, DA, EA, I... (G, H, A, B, C...)	ZINC ION	non-polymer		65.4	16	Chemie (ZN)
3	CA, FA, K, N, Q... (G, H, A, B, C...)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	8	Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 900 (UniProt: P27915)

PDB	External Database	Details
Ala 763	Thr 3253	conflict
-	Trp 3285	deletion
-	Ser 3286	deletion
-	Ile 3287	deletion
-	His 3288	deletion
-	Ala 3289	deletion
-	His 3290	deletion
Ala 901	-	expression tag
Ala 902	-	expression tag
Ala 903	-	expression tag
Leu 904	-	expression tag
Glu 905	-	expression tag
His 906	-	expression tag
His 907	-	expression tag
His 908	-	expression tag
His 909	-	expression tag
His 910	-	expression tag
His 911	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	833119.9
Non-Polymers*	Number of molecules	24
	Total formula weight	4121.8
All*	Total formula weight	837241.7

*Water molecules are not included.