5CCV

Crystal structure of full-length NS5 from dengue virus type 3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	RNA-directed RNA polymerase NS5	polymer	905	104140.0	8	UniProt (P27915) Pfam (PF01728) Pfam (PF00972) Pfam (PF20483) In PDB	Dengue virus type 3 (DENV-3)	Non-structural protein 5
2	G, H, A, B, C...	ZINC ION	non-polymer		65.4	16	Chemie (ZN)
3	G, H, A, B, C...	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	8	Chemie (SAH)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 900 (UniProt: P27915)

PDB	External Database	Details
Ala 763	Thr 3253	conflict
-	Trp 3285	deletion
-	Ser 3286	deletion
-	Ile 3287	deletion
-	His 3288	deletion
-	Ala 3289	deletion
-	His 3290	deletion
Ala 901	-	expression tag
Ala 902	-	expression tag
Ala 903	-	expression tag
Leu 904	-	expression tag
Glu 905	-	expression tag
His 906	-	expression tag
His 907	-	expression tag
His 908	-	expression tag
His 909	-	expression tag
His 910	-	expression tag
His 911	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	833119.9
Non-Polymers*	Number of molecules	24
	Total formula weight	4121.8
All*	Total formula weight	837241.7

*Water molecules are not included.