5CC9
L28F E.coli dihydrofolate reductase complexed with 5,10-dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dihydrofolate reductase | polymer | 159 | 18053.4 | 1 | UniProt (P0ABQ5) Pfam (PF00186) UniProt (by SIFTS) (P0ABQ4) | Escherichia coli | |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | C (A) | 5,10-DIDEAZATETRAHYDROFOLIC ACID | non-polymer | 443.5 | 1 | Chemie (DDF) | |||
| 4 | D (A) | water | water | 18.0 | 239 | Chemie (HOH) |
Sequence modifications
A: 1 - 159 (UniProt: P0ABQ5)
| PDB | External Database | Details |
|---|---|---|
| Phe 28 | Leu 28 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18053.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1186.9 | |
| All* | Total formula weight | 19240.2 |
