5CAY

Envelope glycoprotein gp120 core from HIV type 2 bound to the first two domains of human soluble CD4 receptor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (G)	Envelope glycoprotein gp120 core from ST strain of HIV-2	polymer	345	40380.5	1	Pfam (PF00516) UniProt (by SIFTS) (P20872)	Human immunodeficiency virus type 2 (ISOLATE ST)
2	B (B)	T-cell surface glycoprotein CD4	polymer	190	21248.1	1	UniProt (P01730) Pfam (PF00047) Pfam (PF05790)	Homo sapiens (Human)	T-cell surface antigen T4/Leu-3
3	C (A)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	D (C)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
5	E, F, G, H, I... (G, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	6	Chemie (NAG)

Sequence modifications

B: 1 - 183 (UniProt: P01730)

PDB	External Database	Details
Met 0	-	initiating methionine
His 184	-	expression tag
His 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61628.6
Branched	Number of molecules	2
	Total formula weight	1010.9
Non-Polymers*	Number of molecules	6
	Total formula weight	1327.2
All*	Total formula weight	63966.8

*Water molecules are not included.