5C8W
PKG II's Amino Terminal Cyclic Nucleotide Binding Domain (CNB-A) in a complex with cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | cGMP-dependent protein kinase 2 | polymer | 143 | 16576.9 | 6 | UniProt (Q13237) Pfam (PF00027) | Homo sapiens (Human) | cGK2,cGMP-dependent protein kinase II,cGKII |
| 2 | G, J, K, M, P... (A, B, C, D, E...) | MALONIC ACID | non-polymer | 104.1 | 7 | Chemie (MLA) | |||
| 3 | H, L, N, Q, S... (A, B, C, D, E...) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 6 | Chemie (PCG) | |||
| 4 | I, O, V (A, C, F) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 5 | AA, BA, W, X, Y... (E, F, A, B, C...) | water | water | 18.0 | 712 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 137 - 277 (UniProt: Q13237)
| PDB | External Database | Details |
|---|---|---|
| Gly 135 | - | expression tag |
| Ser 136 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 99461.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2868.6 | |
| All* | Total formula weight | 102330.3 |
