5C8W
PKG II's Amino Terminal Cyclic Nucleotide Binding Domain (CNB-A) in a complex with cGMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | cGMP-dependent protein kinase 2 | polymer | 143 | 16576.9 | 6 | UniProt (Q13237) Pfam (PF00027) | Homo sapiens (Human) | cGK2,cGMP-dependent protein kinase II,cGKII |
| 2 | G, J, K, M, P... (A, B, C, D, E...) | MALONIC ACID | non-polymer | 104.1 | 7 | Chemie (MLA) PubChem (867) | |||
| 3 | H, L, N, Q, S... (A, B, C, D, E...) | CYCLIC GUANOSINE MONOPHOSPHATE | non-polymer | 345.2 | 6 | Chemie (PCG) PubChem (177270406) PubChem (136759845) PubChem (135398570) PubChem (135402012) PubChem (135415582) PubChem (135530416) PubChem (135566687) PubChem (135612771) PubChem (136122637) PubChem (136183234) PubChem (136183235) PubChem (136239427) PubChem (136268916) PubChem (136454903) PubChem (136454906) PubChem (136488083) PubChem (136488088) PubChem (136499047) PubChem (136678837) PubChem (137218937) PubChem (137234705) PubChem (137279777) PubChem (138399475) PubChem (164162904) | |||
| 4 | I, O, V (A, C, F) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) PubChem (923) | |||
| 5 | AA, BA, W, X, Y... (E, F, A, B, C...) | water | water | 18.0 | 712 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 137 - 277 (UniProt: Q13237)
| PDB | External Database | Details |
|---|---|---|
| Gly 135 | - | expression tag |
| Ser 136 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 99461.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2868.6 | |
| All* | Total formula weight | 102330.3 |
