5C6W
anti-CXCL13 scFv - E10
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | H, J | Protein IGHV1-69-2,Ig lambda chain V-II region NIG-84 | polymer | 264 | 27491.0 | 2 | UniProt (A0A0B4J2H0) UniProt (P04209) Pfam (PF07686) UniProt (by SIFTS) (P01704) In PDB | Homo sapiens (Human) | |
| 2 | J, H | CHLORIDE ION | non-polymer | 35.5 | 6 | Chemie (CL) | |||
| 3 | J, H | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | J, H | 1,2-ETHANEDIOL | non-polymer | 62.1 | 29 | Chemie (EDO) | |||
| 5 | J, H | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | water | water | 18.0 | 559 | Chemie (HOH) |
Sequence modifications
H, J: 1 - 98 (UniProt: A0A0B4J2H0)
H, J: 1001 - 1111 (UniProt: P04209)
| PDB | External Database | Details |
|---|---|---|
| Glu 99 | - | linker |
| Pro 100 | - | linker |
| Asp 101 | - | linker |
| Tyr 102 | - | linker |
| Tyr 103 | - | linker |
| Asp 104 | - | linker |
| Ser 105 | - | linker |
| Ser 106 | - | linker |
| Gly 107 | - | linker |
| Tyr 108 | - | linker |
| Tyr 109 | - | linker |
| Pro 110 | - | linker |
| Ile 111 | - | linker |
| Asp 112 | - | linker |
| Ala 113 | - | linker |
| Phe 114 | - | linker |
| Asp 115 | - | linker |
| Ile 116 | - | linker |
| Trp 117 | - | linker |
| Gly 118 | - | linker |
| Gln 119 | - | linker |
| Gly 120 | - | linker |
| Thr 121 | - | linker |
| Thr 122 | - | linker |
| Val 123 | - | linker |
| Thr 124 | - | linker |
| Val 125 | - | linker |
| Ser 126 | - | linker |
| Ser 127 | - | linker |
| Gly 128 | - | linker |
| Gly 129 | - | linker |
| Gly 130 | - | linker |
| Gly 131 | - | linker |
| Ser 132 | - | linker |
| Gly 133 | - | linker |
| Gly 134 | - | linker |
| Gly 135 | - | linker |
| Gly 136 | - | linker |
| Ser 137 | - | linker |
| Gly 138 | - | linker |
| Gly 139 | - | linker |
| Gly 140 | - | linker |
| Gly 141 | - | linker |
| Ser 142 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Ala 1012 | Gly 12 | conflict |
| Ser 1026 | Thr 26 | conflict |
| Ala 1031 | Gly 31 | conflict |
| Trp 1034 | Phe 34 | conflict |
| Phe 1051 | Tyr 51 | conflict |
| Asn 1055 | Ser 55 | conflict |
| Val 1060 | Ile 60 | conflict |
| His 1062 | Asn 62 | conflict |
| Ala 1091 | Ser 91 | conflict |
| - | Phe 93 | deletion |
| Ala 1093 | Thr 94 | conflict |
| Leu 1095 | Thr 96 | conflict |
| Leu 1096 | Asn 97 | conflict |
| Asp 1097 | Ser 98 | conflict |
| Thr 1098 | Arg 99 | conflict |
| Tyr 1099 | Ala 100 | conflict |
| Thr 1103 | Gly 104 | conflict |
| Val 1107 | Leu 108 | conflict |
| Thr 1108 | Ser 109 | conflict |
| Asp 1112 | - | expression tag |
| Gln 1113 | - | expression tag |
| Glu 1114 | - | expression tag |
| Pro 1115 | - | expression tag |
| Lys 1116 | - | expression tag |
| Ser 1117 | - | expression tag |
| Ser 1118 | - | expression tag |
| Asp 1119 | - | expression tag |
| Lys 1120 | - | expression tag |
| Thr 1121 | - | expression tag |
| His 1122 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54981.9 | |
| Non-Polymers* | Number of molecules | 42 |
| Total formula weight | 2705.2 | |
| All* | Total formula weight | 57687.2 |
