5C53
Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase subunit gamma-1 | polymer | 1205 | 135989.5 | 1 | UniProt (P54098) Pfam (PF18136) | Homo sapiens (Human) | Mitochondrial DNA polymerase catalytic subunit,PolG-alpha |
| 2 | B, C (B, C) | Pol gamma B | polymer | 903 | 102458.6 | 2 | Pfam (PF03129) UniProt (by SIFTS) (Q9UHN1) | Homo sapiens | |
| 3 | D (T) | DNA (26-MER) | polymer | 26 | 7955.1 | 1 | DNA launch vector pDE-GFP2 | ||
| 4 | E (P) | DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3') | polymer | 22 | 6795.4 | 1 | DNA launch vector pDE-GFP2 | ||
| 5 | F, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | H (A) | [[(2~{S},5~{R})-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3$l^{4}-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | non-polymer | 489.2 | 1 | Chemie (4Y3) | |||
| 7 | I (P) | 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE | non-polymer | 291.2 | 1 | Chemie (DOC) |
Sequence modifications
A: 35 - 1239 (UniProt: P54098)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 43 | deletion |
| - | Gln 44 | deletion |
| - | Gln 45 | deletion |
| - | Gln 46 | deletion |
| - | Gln 47 | deletion |
| - | Gln 48 | deletion |
| - | Gln 49 | deletion |
| - | Gln 50 | deletion |
| - | Gln 51 | deletion |
| - | Gln 52 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 355657.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 829.0 | |
| All* | Total formula weight | 356486.3 |
