5C51
Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase subunit gamma-1 | polymer | 1205 | 136033.5 | 1 | UniProt (P54098) Pfam (PF18136) | Homo sapiens (Human) | Mitochondrial DNA polymerase catalytic subunit,PolG-alpha |
| 2 | B, C (B, C) | DNA polymerase subunit gamma-2, mitochondrial | polymer | 485 | 54991.0 | 2 | UniProt (Q9UHN1) Pfam (PF03129) | Homo sapiens (Human) | DNA polymerase gamma accessory 55 kDa subunit,p55,Mitochondrial DNA polymerase accessory subunit,MtPolB,PolG-beta |
| 3 | D (P) | DNA (5'-D(*(AD)P*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3') | polymer | 22 | 6779.4 | 1 | Virus Chimp162 | ||
| 4 | E (T) | DNA | polymer | 25 | 7672.9 | 1 | DNA launch vector pDE-GFP2 | ||
| 5 | F, G (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 6 | H (A) | [[(2R,5S)-5-(4-azanyl-5-fluoranyl-2-oxidanylidene-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate | non-polymer | 487.2 | 1 | Chemie (1RY) |
Sequence modifications
A: 35 - 1239 (UniProt: P54098)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 43 | deletion |
| - | Gln 44 | deletion |
| - | Gln 45 | deletion |
| - | Gln 46 | deletion |
| - | Gln 47 | deletion |
| - | Gln 48 | deletion |
| - | Gln 49 | deletion |
| - | Gln 50 | deletion |
| - | Gln 51 | deletion |
| - | Gln 52 | deletion |
| Arg 948 | Ile 948 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 260467.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 535.8 | |
| All* | Total formula weight | 261003.7 |
