5C4V

Ski-like protein

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, C, E)	Mothers against decapentaplegic homolog 4	polymer	258	28294.1	3	UniProt (Q13485) Pfam (PF03166)	Homo sapiens (Human)	Mothers against DPP homolog 4,Deletion target in pancreatic carcinoma 4,SMAD family member 4,hSMAD4
2	D, E, F (B, D, F)	Ski-like protein	polymer	127	14617.8	3	UniProt (P12757) Pfam (PF08782)	Homo sapiens (Human)	Ski-related oncogene,Ski-related protein
3	G (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	H, K, L (B, D, F)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
5	I, J (B)	NICKEL (II) ION	non-polymer		58.7	2	Chemie (NI)
6	M, N, O, P, Q... (A, C, E, B, D...)	water	water		18.0	130	Chemie (HOH)

Sequence modifications

A, C, E: 314 - 549 (UniProt: Q13485)

PDB	External Database	Details
Met 292	-	initiating methionine
His 293	-	expression tag
His 294	-	expression tag
His 295	-	expression tag
His 296	-	expression tag
His 297	-	expression tag
His 298	-	expression tag
Ser 299	-	expression tag
Ser 300	-	expression tag
Gly 301	-	expression tag
Val 302	-	expression tag
Asp 303	-	expression tag
Leu 304	-	expression tag
Gly 305	-	expression tag
Thr 306	-	expression tag
Glu 307	-	expression tag
Asn 308	-	expression tag
Leu 309	-	expression tag
Tyr 310	-	expression tag
Phe 311	-	expression tag
Gln 312	-	expression tag
Ser 313	-	expression tag

B, D, F: 238 - 356 (UniProt: P12757)

PDB	External Database	Details
Met 237	-	initiating methionine
Ala 357	-	expression tag
His 358	-	expression tag
His 359	-	expression tag
His 360	-	expression tag
His 361	-	expression tag
His 362	-	expression tag
His 363	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	128735.7
Non-Polymers*	Number of molecules	6
	Total formula weight	405.7
All*	Total formula weight	129141.4

*Water molecules are not included.